DoxyPEP (doxycycline post-exposure prophylaxis) is an antibiotic taken within 72 hours after condomless sex to significantly reduce the risk of contracting syphilis, chlamydia, and gonorrhea. Following CDC endorsement, it is widely accessible in Florida through affirming providers.

🏥 How to Access DoxyPEP

In Florida, your access route heavily depends on the type of doctor you see.

1. LGBTQ+ Health Clinics (Easiest Access)

Organizations like Care Resource, CAN Community Health, Metro Inclusive Health, and The Center Orlando actively prescribe DoxyPEP. They are familiar with the CDC guidelines and prescribe it routinely for patients who are on PrEP or have a history of bacterial STIs.

2. Telehealth Platforms (Fastest Access)

If you are using a 340B telehealth platform like MISTR or QCarePlus for your PrEP, you can request DoxyPEP directly through their app. This is often the path of least resistance if you live outside a major metropolitan area in Florida.

3. General Practitioners (Variable Success)

If you use a standard primary care doctor, they may not be familiar with DoxyPEP. You may need to advocate for yourself.

Tell your GP: "The CDC recently released guidelines recommending DoxyPEP to prevent bacterial STIs in men who have sex with men. I would like a prescription for doxycycline 200mg to use as post-exposure prophylaxis."

💵 Cost

  • With Insurance: Doxycycline is an old, generic antibiotic. Your standard pharmacy copay applies (typically under $10).
  • Without Insurance: Generic doxycycline is extremely cheap. Using the GoodRx app at a standard Florida pharmacy (like CVS, Walgreens, or Publix) usually brings the cost of a month's supply down to $10–$20.
  • Through Telehealth (340B): If you are receiving care through MISTR or QCarePlus, the medication is often included at zero cost.

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