As of 2026, PEP is provided free of charge in Malta through the public health system.

PEP (Post-Exposure Prophylaxis) must be started as soon as possible after a potential HIV exposure, ideally within 24 hours, and no later than 72 hours. Every hour counts.

🏥 Where to Go

Your destination depends entirely on the time of day:

TimeWhere to go
Weekdays (7:00 am – 1:00 pm)GU Clinic, Mater Dei Hospital (2nd Floor, Outpatients). Go directly to the clinic and state that you need emergency PEP.
Out of hours, weekends, or holidaysAccident & Emergency (A&E), Mater Dei Hospital. The emergency department is open 24/7.

If you are in Gozo, go to the Accident & Emergency department at Gozo General Hospital.

🩺 What to Expect

  1. Assessment: A doctor will assess your risk level to determine if PEP is necessary. They will ask questions about the nature of the exposure (e.g., condom broke, unprotected sex, sexual assault). Be honest so they can provide the correct medical care.
  2. Starter Pack: You will typically be given a starter pack of medication to begin immediately.
  3. Follow-up: If you are seen in A&E, you will be instructed to follow up at the GU Clinic on the next working day to complete your tests and receive the rest of your 28-day prescription.
  4. Testing: You will undergo baseline blood tests for HIV, syphilis, and hepatitis, as well as routine STI screening.

💶 Cost

The medication and all associated medical consultations and tests are free.

⚠️ In Cases of Assault

If your exposure is the result of a sexual assault, please inform the medical staff immediately. They can ensure you receive PEP alongside specialised support, forensic medical care (if you choose), and trauma assistance.

(For detailed information on how PEP medication works in the body and its side effects, see the general PEP Mechanics guide.)

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