PEP (Post-Exposure Prophylaxis) is a 28-day course of emergency HIV medication. It must be started within 72 hours of a high-risk exposure (e.g., a condom break with a partner of unknown status). In Scotland, it is free on the NHS.

🚨 Where to Go Right Now

Your route depends on the time of day. Do not wait for an appointment slot to open up online.

Time / DayWhere to GoWhat to Expect
Weekday (Daytime)Local Health Board Sexual Health ClinicContact Sandyford (Glasgow), Chalmers (Edinburgh), or your local clinic. Call their triage line immediately.
Evening / Weekend / Bank HolidayHospital A&E (Emergency Department)Prepare to wait in triage. Say you need "PEP for sexual exposure."
Unsure where to go?Call NHS 24 on 111NHS 24 will direct you to the nearest open service carrying PEP stock.

Do not go to your GP. General Practices do not stock PEP. They will simply redirect you to A&E, wasting critical hours in your 72-hour window.

🗣️ Navigating A&E Triage

A&E is a high-pressure environment. To ensure you are triaged correctly and efficiently, you need to use clear, explicit language.

  • Use the terminology: Say, "I need an emergency assessment for PEPSE" (Post-Exposure Prophylaxis following Sexual Exposure).
  • State the timeline: "The exposure was [X] hours ago. I know I have a 72-hour window."
  • Be direct about the exposure: State exactly what happened (e.g., receptive anal sex without a condom).

The Starter Pack: A&E will often only give you a 3-to-5-day "starter pack" of PEP. You must attend a sexual health clinic on the next working day. This is mandatory to get the rest of your medication and to complete vital follow-up blood tests.

💊 The Medication: What to Expect

The standard UK PEP regimen usually consists of Truvada (or a generic equivalent) taken alongside either raltegravir or dolutegravir.

  • It is a strict regimen: PEP is a mandatory 28-day course. You cannot miss doses.
  • Side effects are manageable: You may experience nausea, fatigue, or diarrhea. The clinic will often prescribe anti-sickness medication alongside your PEP.
  • Do not stop: Never stop taking PEP without speaking to a doctor first.

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